HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → Ethyl 2-chloro-3-(2-methoxyphenyl)-3-oxopropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | Ethyl (2-methoxybenzoyl)acetate | HCID 2759695 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Ethyl 2-chloro-3-(2-methoxyphenyl)-3-oxopropanoate | HCID 54152211 | 97% |
Reaction Steps
Using ethyl 3-(2-methoxyphenyl)-3-oxopropanoate (1.7 g, 7.4 mmol), sulfuryl chloride (1.2 g, 8.9 mmol) and diethyl ether (100 mL) as starting materials and in the same manner as in Example 20(i), the title compound (1.8 g, 97%) was obtained as colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09139589B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-5af26e72920045898202ee7fd6076789 |
| Source note | uspto-grants-2015_09 |