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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2282242Generated: November 2, 2026

Ethanol → HCID 178427650, compound

https://huagongshe.com/reaction/2282242

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactantp-Toluenesulfonic acidHCID 6101—
ReactantHCID 178433761HCID 178433761—
SolventEthyl AcetateHCID 8857—
ProductHCID 178427650HCID 17842765068.5%

Reaction Steps

The title compound has been prepared according to the similar manner described in 85-B (iv) from 4-[2-({2-methyl-3-[4-phenyl-5-(1H-1,2,4-triazol-3-yl)-1,3-thiazol-2-yl]pyrazolo[1,5-a]pyridin-5-yl}oxy)ethyl]piperazin-2-one (38.0 mg, 0.0759 mmol) and p-toluenesulfonic acid (31.8 mg, 0.167 mmol). The pure title compound (35 mg, 68%) has been obtained as a pale yellow solid by crystallization from EtOH (8 mL) and EtOAc (2 mL).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09139589B2
Source datasetuspto-grants-2015_09
ORD IDord-d52cb8b0da2141e7911623ee95bb5769
Source noteuspto-grants-2015_09