HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-methylbenzenesulfonamide → (E)-2-(2-(4-Bromophenyl)vinylsulfonamido)-5-methylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-methylbenzenesulfonamide | HCID 245584 | — |
| Reactant | (E)-2-(4-bromophenyl)ethene-1-sulfonyl chloride | HCID 23084300 | — |
| Product | (E)-2-(2-(4-Bromophenyl)vinylsulfonamido)-5-methylbenzenesulfonamide | HCID 42644608 | 96% |
Reaction Steps
The title compound was synthesized as described for Example 178 in 96% yield, starting from 2-amino-5-methylbenzenesulfonamide and (E)-2-(4-bromophenyl)ethenesulfonyl chloride (US20040186134 A1). Purification by column chromatography using a gradient of 10-50% ethyl acetate in heptane as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145380B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-023dcfd07f3240ec883cdb5d769e4f20 |
| Source note | uspto-grants-2015_09 |