HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Dimethyl-1-butyne → 2-{2-[4-(3,3-Dimethyl-but-1-ynyl)-phenyl]-ethanesulfonylamino}-5-hydroxymethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Dimethyl-1-butyne | HCID 13512 | — |
| Reactant | 2-[2-(4-Bromo-phenyl)-ethanesulfonylamino]-5-hydroxymethyl-benzenesulfonamide | HCID 57751051 | — |
| Product | 2-{2-[4-(3,3-Dimethyl-but-1-ynyl)-phenyl]-ethanesulfonylamino}-5-hydroxymethyl-benzenesulfonamide | HCID 57751100 | 5% |
Reaction Steps
The title compound was synthesized as described for Example 210 in 5% yield, starting from 2-[2-(4-bromo-phenyl)-ethanesulfonylamino]-5-hydroxymethyl-benzenesulfonamide and 3,3-dimethyl-1-butyne. Purification by preparative HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145380B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-c32a4cf0a2704fa89ba9fd00627cdb59 |
| Source note | uspto-grants-2015_09 |