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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2283376Generated: October 30, 2026

(E)-2-(4-chlorophenyl)ethene-1-sulfonyl chloride → (E)-5-Chloro-2-(2-(4-chlorophenyl)vinylsulfonamido)-4-fluorobenzene sulfonamide

https://huagongshe.com/reaction/2283376

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(E)-2-(4-chlorophenyl)ethene-1-sulfonyl chlorideHCID 5938154—
Reactant2-Amino-5-chloro-4-fluorobenzenesulfonamideHCID 23104228—
Product(E)-5-Chloro-2-(2-(4-chlorophenyl)vinylsulfonamido)-4-fluorobenzene sulfonamideHCID 5775107661%

Reaction Steps

The title compound was synthesized as described for 226 a) in 61% yield, starting from 2-amino-5-chloro-4-fluorobenzenesulfonamide and (E)-2-(4-chlorophenyl)ethenesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09145380B2
Source datasetuspto-grants-2015_09
ORD IDord-2485d03d1a3e40a0876fb68bf4269a8b
Source noteuspto-grants-2015_09