Hydrochloric Acid → HCID 117875382, compound

Participants

Reaction Steps

To (2-{(S)-3-[(R)-1-(3-benzoyl-4-chloro-2-fluoro-phenyl)-propylamino]-butyrylamino}-ethyl)-carbamic acid tert-butyl ester (13 mg, 0.025 mmol) residue was added hydrogen chloride in ethyl acetate (2N, 2 ml). The mixture was stood at room temperature for 20 minutes, diethyl ether was added to precipitate solids. These were isolated by filtration and dried in a vacuum oven to furnish the desired material as a white solid

Provenance & Evidence