Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2283608Generated: October 28, 2026

Trifluoroacetic acid → HCID 86682360, compound

https://huagongshe.com/reaction/2283608

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86682359HCID 86682359—
SolventDichloromethaneHCID 6344—
ProductHCID 86682360HCID 86682360—

Reaction Steps

Trifluoroacetic acid (9 mL) was added to a solution of tert-butyl({5-chloro-2-fluoro-4-[4-fluoro-2-pyridazin-4-yl-5-(trifluoromethyl)phenoxy]phenyl}sulfonyl)1,3-thiazol-4-ylcarbamate (2.0 g, 3.1 mmol) in dichloromethane (20 mL). After 2 hours, the reaction mixture was concentrated in vacuo to afford the title compound as an amber foam (2.37 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09145407B2
Source datasetuspto-grants-2015_09
ORD IDord-09fa563456354647b8497f654f31f0db
Source noteuspto-grants-2015_09