HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86682360, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86682359 | HCID 86682359 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86682360 | HCID 86682360 | — |
Reaction Steps
Trifluoroacetic acid (9 mL) was added to a solution of tert-butyl({5-chloro-2-fluoro-4-[4-fluoro-2-pyridazin-4-yl-5-(trifluoromethyl)phenoxy]phenyl}sulfonyl)1,3-thiazol-4-ylcarbamate (2.0 g, 3.1 mmol) in dichloromethane (20 mL). After 2 hours, the reaction mixture was concentrated in vacuo to afford the title compound as an amber foam (2.37 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145407B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-09fa563456354647b8497f654f31f0db |
| Source note | uspto-grants-2015_09 |