HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-5-methoxypyrimidin-4-amine → 6-(4-(1-(2-(azetidin-1-yl)ethyl)-4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidin-1-yl)-5-methoxypyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-5-methoxypyrimidin-4-amine | HCID 78721 | — |
| Reactant | HCID 71516690 | HCID 71516690 | — |
| Product | 6-(4-(1-(2-(azetidin-1-yl)ethyl)-4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidin-1-yl)-5-methoxypyrimidin-4-amine | HCID 89442481 | — |
Reaction Steps
The title compound was prepared in an analogous manner as 6-(4-(1-(2-(azetidin-1-yl)ethyl)-4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidin-1-yl)-5-isopropoxypyrimidin-4-amine using 6-chloro-5-methoxypyrimidin-4-amine
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145392B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-688fd139356b4abf9dd4c0e5e7479b97 |
| Source note | uspto-grants-2015_09 |