HRID2284057
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
tert-butyl 4-(4-amino-6-(4-(4-(4-fluoro-3-methylphenyl)-1-(2-hydroxyethyl)-1H-imidazol-2-yl)piperidin-1-yl)pyrimidin-5-yl)-1H-pyrazole-1-carboxylate (10.00 mg; 0.02 mmol) in 0.5 ml methanol was added 0.5 ml 4.0M HCl in dioxane, stirred at RT for 3 hrs, showed clean desired by LC-MS. Removed off solvent, got white solid as title compound. LC-MS: (M+1=463, obsd.=463).
WORKUP
后处理
- customRemoved off solvent