Benzenamine, 4-(4-morpholinyl)- → HCID 178507345, compound

HRID 2284228Notes

Reaction equation

HRID 2284228 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[CH:13]=[CH:12][C:10]([NH2:11])=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.[NH2:14][C:15]1[CH:32]=[CH:31][C:18]2[NH:19][C:20]([C:22]3[CH:30]=[CH:29][C:25]([C:26]([O-])=[O:27])=[CH:24][CH:23]=3)=[N:21][C:17]=2[CH:16]=1>>[NH2:14][C:15]1[CH:32]=[CH:31][C:18]2[NH:19][C:20]([C:22]3[CH:23]=[CH:24][C:25]([C:26]([NH:11][C:10]4[CH:12]=[CH:13][C:7]([N:4]5[CH2:3][CH2:2][O:1][CH2:6][CH2:5]5)=[CH:8][CH:9]=4)=[O:27])=[CH:29][CH:30]=3)=[N:21][C:17]=2[CH:16]=1

Participants

3

Reactant 2

HCID 75655Benzenamine, 4-(4-morpholinyl)-HCID 178507346HCID 178507346, compound

Product 1

HCID 178507345HCID 178507345, compound

Procedure

Compound 453 was prepared from 4-morpholinoaniline and 4-(5-amino-1H-benzimidazol-2-yl)benzoate by standard conditions. [M+H]+ calcd for C24H23N5O2: 414.19; found: 413.97.

Sources & evidence

ORD record
ord-f17889c51dc843e5a51144ca051b21d8
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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