Basic information
- CAS
2524-67-6- Standard SMILES
Nc1ccc(N2CCOCC2)cc1- InChIKey
PHNDZBFLOPIMSM-UHFFFAOYSA-N- Molecular formula
- C10H14N2O
- Average molar mass
- 178.23 g/mol
- Monoisotopic mass
- 178.11061307
Names & identifiers
- Preferred name
- Benzenamine, 4-(4-morpholinyl)-
- IUPAC
- 4-morpholin-4-ylaniline
- English name
- 4-Morpholinoaniline
- Molecular formula
- C10H14N2O
- Molecular weight
- 178.23
Names & synonyms
4-MorpholinoanilineN-(4-Aminophenyl)morpholinep-MorpholinoanilineBenzenamine, 4-(4-morpholinyl)-4-Morpholinyl anilineMorpholine, 4-(p-aminophenyl)-EINECS 219-760-1NSC 26334RefChem:561856219-760-12524-67-64-morpholinobenzenamine
Show more names
Clemastine Impurity 6AKOS B025582AKOS BB-8569ASISCHEM Z37706AKOS BBS-00006991ART-CHEM-BB B0255824-MORPHOLIONOANILINE
4-morpholin-4-ylaniline4-(morpholin-4-yl)aniline4-Morpholin-4-yl-phenylamine4-(4-Morpholino)aniline4-(4-Morpholinyl)aniline4-morpholin-4-ylphenylamine86759-37-74-(4-aminophenyl)-morpholine
Database identifiers
- CAS
2524-67-6- PubChem CID
- 75655
- DTXSID
DTXSID8062490- UNII
- 6DRK9JS9QD
- EC Number
- 219-760-1
- Nikkaji
- J39.631A
Properties
Computed structural properties
- XLogP
- 0.7
- Topological polar surface area
- 38.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 1
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 149
Physicochemical properties
- Melting point
- 132 · 132-135 °C(lit.)
- Boiling point
- 310.47 °C · 310.47°C (rough estimate)
- Density
- 1.0777 · 1.0777 (rough estimate)
- refractive index
- 1.525 · 1.5250 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Soluble in chloroform, ethyl acetate.
- pka
- 6.72 · 6.72±0.40(Predicted)
- form
- Crystalline Powder
- color
- Purple to brown
- BRN
- 150957 · 150957
- InChI
- InChI=1S/C10H14N2O/c11-9-1-3-10(4-2-9)12-5-7-13-8-6-12/h1-4H,5-8,11H2
- InChIKey
- PHNDZBFLOPIMSM-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(N2CCOCC2)C=C1
- CAS DataBase Reference
- 2524 · 2524-67-6(CAS DataBase Reference)
- FDA UNII
- 6 DRK9JS9QD · 6DRK9JS9QD
- EPA Substance Registry System
- 4 · 4-(4-Morpholino)aniline (2524-67-6)
- UNSPSC Code
- 12352100 · 12352100
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P264-P271-P280-P302+P352-P305+P351+P338
- target organs
- Respiratory system
- PPE
- 95 · dust mask type N95 (US), Eyeshields, Gloves
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36 · 36/37/38-20/21/22
- Safety Statements
- 26 · 26-37/39-36/37/39-22
- RIDADR
- 2811 · UN2811
- WGK Germany
- 3 · 3
- Hazard Note
- Irritant
- TSCA
- TSCA listed
- HazardClass
- 6.1 · 6.1
- HS Code
- 29349990 · 29349990
- Storage Class
- 11 · 11 - Combustible Solids
- Hazard Classifications
- 2 Skin · Eye Irrit. 2Skin Irrit. 2STOT SE 3
- REACH Registrations
- Active
Safety & regulation
GHS classification
GHS Classification
Warning
H302 (18.5%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 54 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (18.5%)
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- UN2811
- hs_code
- 29349990
- risk_code
- 36/37/38-20/21/22
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi,Xn
- hazard_note
- Irritant
- safety_code
- 26-37/39-36/37/39-22
- hazard_class
- 6.1
- Storage Class
- 11 - Combustible Solids
- target organs
- Respiratory system
- Hazard statements
- H315-H319-H335
- REACH Registrations
- Active
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationBenzenamine, 4-(4-morpholinyl)-: ACTIVE
Applications
Uses4-(4-Morpholinyl)aniline is used in the preparation of central nervous system (CNS) active agents, also used in the color developing process in photographs.
Uses4-Morpholinoaniline is a morpholine derivative used in the preparation of central nervous system (CNS) active agents. 4-Morpholinoaniline is also one of the primary aromatic amines used in the colour developing process in photographs.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]
Ark Pharm, Inc.847-367-3680 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
北京华威锐科化工有限公司0757-86329057 18934348241 · [email protected]
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上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
上海相辉医药科技有限公司13761987713 · [email protected]
上海星酶生物科技有限公司18112588827
Zhejiang J&C Biological Technology Co.,Limited+1-2135480471 · [email protected]
上海攀鸿化工科技有限公司021-56491756 13512199871 · [email protected]
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四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
上海法默生物科技有限公司02136680027 15800370750 · [email protected]
苏州岚云医药科技有限公司2332782371 · [email protected]
深圳法默科技有限公司0755-86648230 · [email protected]
上海先诺生物科技有限公司021-50718719 13918719472
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江苏艾康生物医药研发有限公司025-66113011 13913916777 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
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越林试剂021-62960152 · [email protected]
上海汇凯化学科技有限公司021-61995394 18916691159 · [email protected]
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上海泽信化工科技有限公司021-60136491 15901897992
CEG Chemical Science & Technology Co., Ltd.Mobile:13665161512
苏州爱玛特生物科技有限公司0512-56316828 4008675858 · [email protected]
上海湄水化工科技有限公司021-60549325 18616193163
上海将来实业股份有限公司021-61552785 · [email protected]
HBCChem, Inc.+1-510-219-6317 · [email protected]
Labnetwork lnc.+86-27-50766799 +86-18062016861 · [email protected]
上海馨远医药科技有限公司021-24206007 13764915196 · [email protected]
上海鑫圭生物科技有限公司15121041756 · [email protected]
Related reactions
325 records
Compound notes
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