Benzenamine, 4-(4-morpholinyl)- → HCID 178474063, compound

HRID 2284229Notes

Reaction equation

HRID 2284229 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[CH:13]=[CH:12][C:10]([NH2:11])=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.[NH:14]([C:18]1[CH:35]=[CH:34][C:21]2[NH:22][C:23]([C:25]3[CH:33]=[CH:32][C:28]([C:29]([O-])=[O:30])=[CH:27][CH:26]=3)=[N:24][C:20]=2[CH:19]=1)[C:15]([CH3:17])=[O:16]>>[NH:14]([C:18]1[CH:35]=[CH:34][C:21]2[NH:22][C:23]([C:25]3[CH:33]=[CH:32][C:28]([C:29]([NH:11][C:10]4[CH:12]=[CH:13][C:7]([N:4]5[CH2:3][CH2:2][O:1][CH2:6][CH2:5]5)=[CH:8][CH:9]=4)=[O:30])=[CH:27][CH:26]=3)=[N:24][C:20]=2[CH:19]=1)[C:15]([CH3:17])=[O:16]

Participants

3

Reactant 2

HCID 75655Benzenamine, 4-(4-morpholinyl)-HCID 178474064HCID 178474064, compound

Product 1

HCID 178474063HCID 178474063, compound

Procedure

Compound 454 was prepared from 4-morpholinoaniline and 4-(5-acetamino-1H-benzimidazol-2-yl)benzoate by standard conditions. [M+H]+ calcd for C26H25N5O3: 456.20; found: 455.95.

Sources & evidence

ORD record
ord-4d8bd8bd69c747d899e0a825e7e42dbc
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

Loading…