Benzenamine, 4-(4-morpholinyl)- → HCID 178522200, compound

HRID 2284247Notes

Reaction equation

HRID 2284247 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[CH:13]=[CH:12][C:10]([NH2:11])=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.[F:14][C:15]([F:36])([F:35])[O:16][C:17]1[CH:34]=[CH:33][C:20]2[NH:21][C:22]([C:24]3[CH:32]=[CH:31][C:27]([C:28]([O-])=[O:29])=[CH:26][CH:25]=3)=[N:23][C:19]=2[CH:18]=1>>[F:36][C:15]([F:14])([F:35])[O:16][C:17]1[CH:34]=[CH:33][C:20]2[NH:21][C:22]([C:24]3[CH:32]=[CH:31][C:27]([C:28]([NH:11][C:10]4[CH:12]=[CH:13][C:7]([N:4]5[CH2:3][CH2:2][O:1][CH2:6][CH2:5]5)=[CH:8][CH:9]=4)=[O:29])=[CH:26][CH:25]=3)=[N:23][C:19]=2[CH:18]=1

Participants

3

Reactant 2

HCID 75655Benzenamine, 4-(4-morpholinyl)-HCID 178524239HCID 178524239, compound

Product 1

HCID 178522200HCID 178522200, compound

Procedure

Compound 481 was prepared from 4-morpholinoaniline and 4-(5-trifluoromethoxy-1H-benzimidazol-2-yl)benzoate by standard conditions. [M+H]+ calcd for C25H21F3N4O3: 483.17; found: 482.93.

Sources & evidence

ORD record
ord-f851af0a93864065a8e19b69d32bf007
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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