HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Hydroxy-1-piperidinyl)benzoic acid → N-(4-((4-Amino-2-fluorophenyl)amino)phenyl)-4-(4-hydroxypiperidin-1-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Hydroxy-1-piperidinyl)benzoic acid | HCID 18617591 | — |
| Reactant | N1-(4-aminophenyl)-2-fluorobenzene-1,4-diamine | HCID 86674024 | — |
| Product | N-(4-((4-Amino-2-fluorophenyl)amino)phenyl)-4-(4-hydroxypiperidin-1-yl)benzamide | HCID 67112608 | — |
Reaction Steps
Compound 807 was prepared according to the procedure described in Scheme IV from N1-(4-aminophenyl)-2-fluorobenzene-1,4-diamine and 4-(4-hydroxypiperidin-1-yl)benzoic acid. [M+H]+ calcd for C24H25FN4O2: 421.20; found 420.98.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09144557B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-bf4e0f0849764032ad1a07aa2851b491 |
| Source note | uspto-grants-2015_09 |