HRID2284305

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID18617591

4-(4-Hydroxy-1-piperidinyl)benzoic acid

C12H15NO3

HCID86674025

未命名化合物

PRODUCTS

生成物

结构：O=C(Nc1ccc(Nc2ccc(NC(=O)c3ccc(N4CCC(O)CC4)cc3)cc2Cl)cc1)c1ccc(N2CCC(O)CC2)cc1

HCID67114493

未命名化合物

PROCEDURE

实验过程

Compound 826 was prepared according to the procedure described in Scheme IV from N1-(4-aminophenyl)-2-chlorobenzene-1,4-diamine and 4-(4-hydroxypiperidin-1-yl)benzoic acid. [M+H]+ calcd for C36H38ClN5O4: 640.26; found 640.12.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-430be2ee5c414454a11e85572752cd1c
来源数据集: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09144557B2
来源说明: uspto-grants-2015_09

反应 SMILES

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([NH2:15])=[CH:11][C:10]=2[Cl:16])=[CH:4][CH:3]=1.[OH:17][CH:18]1[CH2:23][CH2:22][N:21]([C:24]2[CH:32]=[CH:31][C:27]([C:28](O)=[O:29])=[CH:26][CH:25]=2)[CH2:20][CH2:19]1>>[Cl:16][C:10]1[CH:11]=[C:12]([NH:15][C:28](=[O:29])[C:27]2[CH:31]=[CH:32][C:24]([N:21]3[CH2:22][CH2:23][CH:18]([OH:17])[CH2:19][CH2:20]3)=[CH:25][CH:26]=2)[CH:13]=[CH:14][C:9]=1[NH:8][C:5]1[CH:4]=[CH:3][C:2]([NH:1][C:28](=[O:29])[C:27]2[CH:26]=[CH:25][C:24]([N:21]3[CH2:22][CH2:23][CH:18]([OH:17])[CH2:19][CH2:20]3)=[CH:32][CH:31]=2)=[CH:7][CH:6]=1