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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2284305Generated: October 31, 2026

4-(4-Hydroxy-1-piperidinyl)benzoic acid → N-(3-Chloro-4-((4-(4-(4-hydroxypiperidin-1-yl)benzamido)phenyl)amino)phenyl)-4-(4-hydroxypiperidin-1-yl)benzamide

https://huagongshe.com/reaction/2284305

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Hydroxy-1-piperidinyl)benzoic acidHCID 18617591—
ReactantN1-(4-aminophenyl)-2-chlorobenzene-1,4-diamineHCID 86674025—
ProductN-(3-Chloro-4-((4-(4-(4-hydroxypiperidin-1-yl)benzamido)phenyl)amino)phenyl)-4-(4-hydroxypiperidin-1-yl)benzamideHCID 67114493—

Reaction Steps

Compound 826 was prepared according to the procedure described in Scheme IV from N1-(4-aminophenyl)-2-chlorobenzene-1,4-diamine and 4-(4-hydroxypiperidin-1-yl)benzoic acid. [M+H]+ calcd for C36H38ClN5O4: 640.26; found 640.12.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09144557B2
Source datasetuspto-grants-2015_09
ORD IDord-430be2ee5c414454a11e85572752cd1c
Source noteuspto-grants-2015_09