反应详情

温度

90 °C

To concentrated sulfuric acid (275 mL) at 50° C. was added N-(3-bromo-phenyl)-2-hydroxyimino-acetamide (55 g, 0.2272 mol). The temperature was raised to 90° C. and maintained for 3 hours. The reaction mixture was added to ice cold water to provide a yellow precipitate. The precipitate was filtered and dried to provide the title compound as a yellow solid (50 g, 98%). This material was taken for next step without any further purification.

1. temperaturemaintained for 3 hours
2. additionThe reaction mixture was added to ice cold water
3. customto provide a yellow precipitate
4. filtrationThe precipitate was filtered
5. customdried