HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-{[(3-aminophenyl)carbamoyl]methyl}carbamate → Tert-butyl (2-((3-(2-((4-cyanophenyl)amino)-4-(propylamino)pyrimidine-5-carboxamido)phenyl)amino)-2-oxoethyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-{[(3-aminophenyl)carbamoyl]methyl}carbamate | HCID 68275132 | — |
| Reactant | 2-((4-Cyanophenyl)amino)-4-(propylamino)pyrimidine-5-carboxylic acid | HCID 90052036 | — |
| Product | Tert-butyl (2-((3-(2-((4-cyanophenyl)amino)-4-(propylamino)pyrimidine-5-carboxamido)phenyl)amino)-2-oxoethyl)carbamate | HCID 90051987 | — |
Reaction Steps
By using tert-butyl (2-((3-aminophenyl)amino)-2-oxoethyl)carbamate (B1) and 2-((4-cyanophenyl)amino)-4-(propylamino)pyrimidine-5-carboxylic acid (C5), tert-butyl (2-((3-(2-((4-cyanophenyl)amino)-4-(propylamino)pyrimidine-5-carboxamido)phenyl)amino)-2-oxoethyl)carbamate (D8) was obtained in the same manner as that of Example 12, (1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145415B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-a8748bd8bc7e41d5b0662145a01d8e1b |
| Source note | uspto-grants-2015_09 |