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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2284731Generated: November 2, 2026

Toluene → HCID 178449832, compound

https://huagongshe.com/reaction/2284731

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantSodium SulfateHCID 24436—
Reactanttert-butyl N-(2-amino-2-methylpropyl)carbamateHCID 17909918—
SolventBenzaldehydeHCID 240—
ProductHCID 178449832HCID 178449832—

Reaction Steps

To a suspension of tert-butyl (2-amino-2-methylpropyl)carbamate (1.98 g) and anhydrous sodium sulfate (3.00 g) in toluene (5 mL), benzaldehyde (1.07 mL) was added at room temperature, and the mixture was stirred for 11 hours under reflux by heating. The reaction mixture was cooled to room temperature, and then the solvent was evaporated under reduced pressure to obtain (E)-tert-butyl (2-(benzylideneamino)-2-methylpropyl)carbamate (G8).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09145415B2
Source datasetuspto-grants-2015_09
ORD IDord-0db8ab7d317b42abb605884a8f0e2d1d
Source noteuspto-grants-2015_09