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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 228524Generated: October 27, 2026

Hydrochloride methanol → 6,7-Dimethoxy-4-(3,4-dimethylphenoxy)quinoline hydrochloride

https://huagongshe.com/reaction/228524

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloride methanolHCID 21893726—
Reactant6,7-Dimethoxy-4-(3,4-dimethylphenoxy)quinolineHCID 23078387—
Product6,7-Dimethoxy-4-(3,4-dimethylphenoxy)quinoline hydrochlorideHCID 2307854587%

Reaction Steps

6,7-Dimethoxy-4-(3,4-dimethylphenoxy)quinoline (122 mg) was dissolved in a 10% hydrochloric acid/methanol solution, and the solution was stirred at room temperature for 15 min. The solvent was removed therefrom by distillation under the reduced pressure. The residue was washed with ethyl acetate to give the title compound (118 mg, yield 87%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560558B2
Source datasetuspto-grants-2009_07
ORD IDord-d4b6650a7ad546d89649f5741e9d45db
Source noteuspto-grants-2009_07