HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyano-2-methyl-but-3-enoic acid tert-butyl ester → 2-Cyano-2-methyl-but-3-enoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyano-2-methyl-but-3-enoic acid tert-butyl ester | HCID 86709662 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Cyano-2-methyl-but-3-enoic acid | HCID 86709663 | — |
Reaction Steps
2-Cyano-2-methyl-but-3-enoic acid tert-butyl ester (362 mg, 2 mmol) was suspended in 4 M hydrochloric acid in dioxane (10 mL) and the reaction mixture stirred for 38 h and then evaporated. The residue was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145441B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-56f37af3f8c64a289aacb23f75ee8d6c |
| Source note | uspto-grants-2015_09 |