Sodium Methoxide → HCID 70546260, compound

Participants

Reaction Steps

3 g 4-chloro-2-methyl-6-methylthio-5-(2-imidazolin-2-yl)-aminopyrimidine (Example 2) are mixed with 60 ml 15% methanolic sodium methylate solution and boiled for 4 hours under reflux. Then about 40 ml methanol are distilled off. The solution is mixed with water and cooled until it crystallizes. 1.5 g of 4-methoxy-2-methyl-6-methylthio-5-(2-imidazolin-2-yl)-aminopyrimidine is obtained, (Melting point 267° C.) after recrystallization from nitromethane.

Provenance & Evidence