Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | HCID 178516636 | HCID 178516636 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178526880 | HCID 178526880 | — |
Reaction Steps
To 128.8 ml acetic acid are added 50.57 ml fuming nitric acid without exceeding 20° C. 57 g (0.375 mole) 2-cyclopropyl-4,6-dihydroxy-pyrimidine are added in portions without exceeding a temperature of 15° C. Then the reaction mixture is stirred for half an hour at 15° C., mixed with ice, and the deposit is washed with lots of water and dried. 69.8 of 2-cyclopropyl-4,6-dihydroxy-5-nitro-pyrimidine is obtained. Melting point 230°-235° C. (decomp.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04323570 |
|---|
| Source dataset | uspto-grants-1982_04 |
|---|
| ORD ID | ord-4e043d614b374ad6b0c8a3232cb7761c |
|---|
| Source note | uspto-grants-1982_04 |
|---|
