反应详情

A mixture of 200 g of but-3-yn-2-ol and 240 g of ethylvinyl ether was added dropwise, at 30° and under nitrogen atmosphere, to 2 g of previously dried KHSO4. After stirring for 2 hours at 30° the reaction mixture was neutralized with 10 g of Na2CO3, then filtered, the organic phase being finally distilled on a VIGREUX column to give 369 g (91% yield) of 2-(3-oxa-pent-2-yloxy)-but-3-yne having b.p. 31°/16 Torr.

1. filtrationfiltered
2. distillationthe organic phase being finally distilled on a VIGREUX column