HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Sodium 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate | HCID 54217 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Sodium 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate | HCID 23676477 | — |
Reaction Steps
A mixture of 8.05 g of 2-[5-(4-chlorophenyl)pentyl]oxirane 2-carboxylic acid ethyl ester, 27 ml of tetrahydrofuran and 27 ml of 1 N sodium hydroxide solution is stirred for about 1 hour until a clear solution has formed. The solution is concentrated and the colorless residue is recrystallized from ethanol/diethyl ether. 6.5 g of the title compound of m.p. 136° to 142° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04324796 |
| Source dataset | uspto-grants-1982_04 |
| ORD ID | ord-237367ec042646e1a75527e0dfebf599 |
| Source note | uspto-grants-1982_04 |