Thionyl Chloride → HCID 12932087, compound

HRID 2285756Notes

Reaction equation

HRID 2285756 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:12][CH3:13])=[C:6]([CH2:8][CH2:9][CH2:10]O)[CH:7]=1.S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:12][CH3:13])=[C:6]([CH2:8][CH2:9][CH2:10][Cl:16])[CH:7]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 2667453-(5-chloro-2-methoxyphenyl)propan-1-ol

Product 1

HCID 12932087HCID 12932087, compound

Procedure

58.2 g of 3-(5-chloro-2-methoxyphenyl)propan-1-ol and 50 ml of thionyl chloride are stirred at 50° for 8 hours; the excess thionyl chloride is distilled off in vacuo and the residue is distilled under a high vacuum. 50.9 g of 3-(5-chloro-2-methoxyphenyl)propyl chloride of b.p. 87° to 95° under 0.005 mm Hg are obtained.

Workup

  1. distillationthe excess thionyl chloride is distilled off in vacuo
  2. distillationthe residue is distilled under a high vacuum

Sources & evidence

ORD record
ord-1e7a2a9b6b184db8ae0b8e151812eaa5
Source dataset
uspto-grants-1982_04
Patent number
US04324796

Reaction notes

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