Hydrogen Bromide → HCID 20544211, compound

HRID 2285757Notes

Reaction equation

HRID 2285757 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]O)=[CH:4][CH:3]=1.[BrH:16].S(=O)(=O)(O)O>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][Br:16])=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 1118Sulfuric AcidHCID 20544219HCID 20544219, compound

Product 1

HCID 20544211HCID 20544211, compound

Procedure

30 g of 7-(4-chlorophenyl)heptan-1-ol, 0.13 g of red phosphorus and 37 ml of 62% strength hydrogen bromide are boiled for 6 hours, 8 ml of concentrated sulfuric acid are then added dropwise and the mixture is boiled again for 6 hours. The reaction mixture is poured into 100 ml of ice-water and is extracted twice with diethyl ether; the ether extracts are concentrated and the residue is distilled. 33.5 g of 7-(4-chlorophenyl)heptyl bromide of b.p. 125° to 127° under 0.1 mm Hg are obtained.

Workup

  1. extractionis extracted twice with diethyl ether
  2. concentrationthe ether extracts are concentrated
  3. distillationthe residue is distilled

Sources & evidence

ORD record
ord-f0756cc60aa142d18b72a82b56dc0f20
Source dataset
uspto-grants-1982_04
Patent number
US04324796

Reaction notes

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