反应详情

Diphenylphosphino lithium was prepared by adding n-butyl lithium (12.5 ml, 1.6 molar, 0.02 mole) in hexane to a solution of chlorodiphenylphosphine (3.76 g, 0.02 mole) in tetrahydrofuran. The dibromopropyl carbon of step 2 was added and the mixture was stirred for 15 hours. Water (100 ml) was added and the mixture stirred for 15 hours. Water (100 ml) was added and the product filtered. After washing with tetrahydrofuran and drying at 55° C. and 0.1 mm Hg pressure for three hours, the product contained 1.24 wt. % phosphorus.

1. stirringthe mixture stirred for 15 hours
2. filtrationthe product filtered
3. washAfter washing with tetrahydrofuran
4. customdrying at 55° C.
5. wait0.1 mm Hg pressure for three hours