Water → HCID 178418495, compound

HRID 2285872Notes

Reaction equation

HRID 2285872 reaction equation
C([Li:5])CCC.Cl[P:7]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.BrC(Br)CC[C].O>CCCCCC.O1CCCC1>[C:8]1([P:7]([Li:5])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

7

Reactant 4

HCID 962Water2×HCID 66180ChlorodiphenylphosphineHCID 178418339ButyllithiumHCID 178440535HCID 178440535, compound

Product 1

HCID 178418495HCID 178418495, compound

Reagents, catalysts & solvents 2

HCID 8028TetrahydrofuranSolventHCID 8058HexaneSolvent

Procedure

Diphenylphosphino lithium was prepared by adding n-butyl lithium (12.5 ml, 1.6 molar, 0.02 mole) in hexane to a solution of chlorodiphenylphosphine (3.76 g, 0.02 mole) in tetrahydrofuran. The dibromopropyl carbon of step 2 was added and the mixture was stirred for 15 hours. Water (100 ml) was added and the mixture stirred for 15 hours. Water (100 ml) was added and the product filtered. After washing with tetrahydrofuran and drying at 55° C. and 0.1 mm Hg pressure for three hours, the product contained 1.24 wt. % phosphorus.

Workup

  1. stirringthe mixture stirred for 15 hours
  2. filtrationthe product filtered
  3. washAfter washing with tetrahydrofuran
  4. customdrying at 55° C.
  5. wait0.1 mm Hg pressure for three hours

Sources & evidence

ORD record
ord-cdf31f1da3ad4667962493c0a97a1a0c
Source dataset
uspto-grants-1982_04
Patent number
US04325834

Reaction notes

Loading…