Triethylamine → HCID 12834418, compound

HRID 2285921Notes

Reaction equation

HRID 2285921 reaction equation
[CH3:1][O:2][C:3]([C:5]1[C:6](C)=[CH:7][CH:8]=[C:9](CBr)[CH:10]=1)=[O:4].[SH:14][C:15]1[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=1.[CH2:21](N(CC)CC)C>C1(C)C=CC=CC=1>[N:18]1[CH:19]=[CH:20][C:15]([S:14][CH2:21][C:8]2[CH:9]=[CH:10][C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:6][CH:7]=2)=[CH:16][CH:17]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 86212244501362-17-0HCID 178418431pyridine-4-thiol

Product 1

HCID 12834418HCID 12834418, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture containing 11.0 grams of methyl-p-(bromomethyl)toluate (0.048 mole), 5.3 grams of 4-mercaptopyridine (0.048 mole), 25 ml of triethylamine and 200 ml of toluene was refluxed for 16 hours and then cooled to room temperature. The reaction mixture was washed twice with 300 ml of water. The toluene layer was dried over anhydrous sodium sulfate and then concentrated to give a dark red oil which solidified upon cooling.

Workup

  1. temperaturewas refluxed for 16 hours
  2. washThe reaction mixture was washed twice with 300 ml of water
  3. dry with materialThe toluene layer was dried over anhydrous sodium sulfate
  4. concentrationconcentrated
  5. customto give a dark red oil which
  6. temperatureupon cooling

Sources & evidence

ORD record
ord-01fe414da9584033a2aa3092daff022d
Source dataset
uspto-grants-1982_04
Patent number
US04325959

Reaction notes

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