反应详情

A mixture of 19.5 ml (0.15 mol) of 4-chlorobenzylmercaptan, 27.1 g (0.15 mol) of ethyl α-bromopropionate, 21 g of potassium carbonate and 0.1 g of potassium iodide in 100 ml of anhydrous acetone is maintained under reflux for 6 hours. The mixture is filtered, the precipitate is washed with acetone and the filtrate is evaporated in vacuo. 200 ml of ether are added to the residue and the ether solution is washed with dilute NaOH, dilute HCl and water.

1. temperatureis maintained
2. temperatureunder reflux for 6 hours
3. filtrationThe mixture is filtered
4. washthe precipitate is washed with acetone
5. customthe filtrate is evaporated in vacuo
6. addition200 ml of ether are added to the residue
7. washthe ether solution is washed with dilute NaOH, dilute HCl and water