反应详情

To a solution containing 15.0 g. of 6,7-dimethoxy-2-naphthoic acid and one drop of dimethylformamide in 200 ml. of benzene was added 25 ml. of thionyl chloride. After heating one hour under reflux the mixture was evaporated to dryness in vacuo. Additional benzene was added and evaporation repeated to give 6,7-dimethoxy-2-naphthoyl chloride which was used directly in the preparation of 6,7-dimethoxy-2-naphthamide as described hereinabove in Example 113.

1. additionTo a solution containing 15.0 g
2. temperatureAfter heating one hour
3. temperatureunder reflux the mixture
4. customwas evaporated to dryness in vacuo
5. additionAdditional benzene was added
6. customevaporation