Formaldehyde → HCID 15575063, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2.08 g 3,5-dioxo-4-propargyl-2,3,4,5-tetrahydro-1,2,4-triazine, 4.1 ml 35% aqueous formalin, 0.78 g potassium hydroxide and 7 ml water was stirred at 50° C. for 4 hours. After cooling to room temperature, the reaction solution was neutralized to a pH of 7 with acetic acid and extracted with three 30-ml portions of chloroform. The chloroform layers were combined, washed with 10 ml sodium chloride-saturated water and dried over magnesium sulfate. Chloroform was concentrated under reduced pressure to obtain a pale yellow semi-solid.

Provenance & Evidence