Phenyl chloroformate → HCID 20542235, compound

Participants

Reaction Steps

By reacting phenyl chloroformate (16.7 g) with 7-(5-chloropyrid-2-yl)-6-hydroxy-3-methoxy-8-oxo-3,4,7,8-tetrahydro-2H,6H-1,4-dithiepino[2,3-c]-pyrrole (prepared as described in Example 1; 12.3 g) in anhydrous pyridine (100 cc) at between -10° C. and +20° C., 7-(5-chloropyrid-2-yl)-3-methoxy-8-oxo-6-phenoxycarbonyloxy-3,4,7,8-tetrahydro-2H,6H-1,4-dithiepino[2,3-c]pyrrole (m.p. 167° C.; 10.1 g) is obtained.

Provenance & Evidence