HCID 15571067, compound → HCID 15571068, compound

HRID 2286246Notes

Reaction equation

HRID 2286246 reaction equation
[CH3:1][O:2][CH:3]([O:18][CH3:19])[CH2:4][NH:5][C:6](=[O:17])[CH:7]([CH2:12][S:13]C(=O)C)[CH2:8][CH:9]([CH3:11])[CH3:10]>C(O)C>[CH3:19][O:18][CH:3]([O:2][CH3:1])[CH2:4][NH:5][C:6](=[O:17])[CH:7]([CH2:12][SH:13])[CH2:8][CH:9]([CH3:10])[CH3:11]

Participants

3

Reactant 1

HCID 15571067HCID 15571067, compound

Product 1

HCID 15571068HCID 15571068, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The N-(2,2-dimethoxyethyl)-2-[(acetylthio)methyl]-4-methylpentanamide obtained in Example 1 is dissolved in 15 ml of absolute ethanol and the atmosphere is purged with argon. Concentrated ammonium hydroxide (2 ml) is added and this solution is stirred at room temperature for 3 hours, concentrated to dryness in vacuo and dried at 50° C. for 8 hours over phosphorous pentoxide. The title compound (0.8 g) crystallizes, melting point 34°-37° C.

Workup

  1. customthe atmosphere is purged with argon
  2. additionConcentrated ammonium hydroxide (2 ml) is added
  3. concentrationconcentrated to dryness in vacuo
  4. dry with materialdried at 50° C. for 8 hours over phosphorous pentoxide
  5. customThe title compound (0.8 g) crystallizes

Sources & evidence

ORD record
ord-6f8d087d906b4acda69ef7210964a8fb
Source dataset
uspto-grants-1982_04
Patent number
US04327111

Reaction notes

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