Methylamine → HCID 53801169, compound

Participants

Reaction Steps

Z-α-methoxyimino-2-pyridineacetic acid methylester (5 g) and a solution of methylamine in water (15 ml, 30%) were stirred at a temperature of 60° C. until the starting compound was completely dissolved. Water was evaporated under reduced pressure and the residue was recrystallized from toluene, yielding N-methyl-α-methoxyimino-2-pyridineacetamide (3.0 g), Z-isomer, m.p. 132°-133° C. The E-isomer was obtained in the same way, but starting from the corresponding E-ester. M.p. of the E-isomer 91°-93° C.

Provenance & Evidence