Acetone → HCID 13060841, compound

Participants

Reaction Steps

A mixture of 10.0 g (0.05 m.) 2-mercapto-thiazole-4-acetic acid, ethyl ester (prepared according to U.S. Pat. No. 2,766,238) and 10.75 g. (0.05 m.) α-bromophenylacetic acid in 200 ml. of acetone and 20 ml. each of glacial acetic acid and acetic anhydride is heated in an open flask for two hours. The solvents are removed and the residual solid triturated with acetone. 12 g. of title product is obtained, m.p. 160°-170° C. (dec.).

Provenance & Evidence