4-tert-Butylbenzoyl chloride → HCID 21464702, compound

HRID 2286297Notes

Reaction equation

HRID 2286297 reaction equation
[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9](Cl)=[O:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].C[O:15][P:16]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.CC(CC(C1C(O)=CC(O)=C(CC=C(C)C)C=1[O-])=O)C>C1(C)C=CC=CC=1>[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9]([P:16](=[O:15])([C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 743724-tert-Butylbenzoyl chlorideHCID 77636MethoxydiphenylphosphineHCID 252006104-Prenylphlorisovalerophenone

Product 1

HCID 21464702HCID 21464702, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

41.3 parts of p-tert.-butylbenzoyl chloride are reacted with 45.4 parts of methoxydiphenylphosphine, dissolved in 20 parts of toluene, in 90 minutes at 50° C., by a method similar to that described for compound X. After evaporating off the solvent on a rotary evaporator, the product is recrystallized from cyclohexane.

Workup

  1. customAfter evaporating off the solvent
  2. customon a rotary evaporator
  3. customthe product is recrystallized from cyclohexane

Sources & evidence

ORD record
ord-e26c18fde59d48ffada3484bfff8cdd1
Source dataset
uspto-grants-1981_05
Patent number
US04265723

Reaction notes

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