Hydrochloric Acid → Diethyl (1-methyl-3-oxocyclohexyl)phosphonate

HRID 2286303Notes

Reaction equation

HRID 2286303 reaction equation
[CH2:1]([O:3][P:4]([O-:8])[O:5][CH2:6][CH3:7])[CH3:2].[CH3:9][C:10]1[CH2:15][CH2:14][CH2:13][C:12](=[O:16])[CH:11]=1.Cl>>[CH3:9][C:10]1([P:4]([O:5][CH2:6][CH3:7])(=[O:8])[O:3][CH2:1][CH3:2])[CH2:11][C:12](=[O:16])[CH2:13][CH2:14][CH2:15]1.[CH3:9][C:10]1([P:4]([OH:3])(=[O:5])[OH:8])[CH2:11][C:12](=[O:16])[CH2:13][CH2:14][CH2:15]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 145113-Methyl-2-cyclohexen-1-oneHCID 3780918Diethylphosphite

Product 2

HCID 15315829Diethyl (1-methyl-3-oxocyclohexyl)phosphonateHCID 54130000HCID 54130000, compound

Procedure

Diethyl 1-methyl-5-oxocyclohexanephosphonate (B.Pt. 130°-2°/0.8 mm) was prepared by the base catalysed addition of diethylphosphite to 3-methyl-2-cyclohexen-1-one. Hydrolysis of this ester with concentrated HCl gave 1-methyl-5-oxocyclohexanephosphonic acid as a viscous oil.

Sources & evidence

ORD record
ord-9cf1dfad26524899b13ab2fee1749c4e
Source dataset
uspto-grants-1981_05
Patent number
US04265769

Reaction notes

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