Water → HCID 23463047, compound

Participants

Reaction Steps

12 g of 2-(2-cyanophenyl)-6-phenyl-imidazo[2,1-b]-1,3,4-thiadiazole (Example No. 31) are heated to 170°-175° C. in 40 g of crystalline H3PO4 for 5 hours, the mixture is cooled and stirred with water, the precipitate is filtered off and dissolved in 2 N NaOH, the solution is clarified with charcoal and the product is precipitated with 2 N HCl.

Provenance & Evidence