Urea → Tetrakis(ureidomethyl)phosphonium chloride

HRID 2286379Notes

Reaction equation

HRID 2286379 reaction equation
[CH2:1]([P+:3]([CH2:8]O)([CH2:6]O)[CH2:4]O)O.[Cl-:10].[NH2:11][C:12]([NH2:14])=[O:13]>C1(C)C=CC=CC=1>[Cl-:10].[NH:11]([CH2:8][P+:3]([CH2:1][NH:11][C:12]([NH2:14])=[O:13])([CH2:4][NH:11][C:12]([NH2:14])=[O:13])[CH2:6][NH:11][C:12]([NH2:14])=[O:13])[C:12]([NH2:14])=[O:13]

Participants

4

Reactant 2

HCID 1176UreaHCID 31298Tetrakis(hydroxymethyl)phosphonium chloride

Product 1

HCID 23463266Tetrakis(ureidomethyl)phosphonium chlorideYield 101.1%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Reaction of THPC (9.53 g, 0.05 mol) with urea (12.01 g, 0.2 mol) in toluene (75 ml), following Example 1, gave 18.14 g (101%) of tetrakis(ureidomethyl)phosphonium chloride (I, R=R'=R"=H, X=Cl) as a colorless, brittle glass.

Sources & evidence

ORD record
ord-4d0fb1169bc844f187615b8e5fa7b793
Source dataset
uspto-grants-1981_05
Patent number
US04265945

Reaction notes

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