2-Furanmethanethiol → HCID 23462916, compound

HRID 2286408Notes

Reaction equation

HRID 2286408 reaction equation
[CH2:1]([SH:7])[C:2]1[O:6][CH:5]=[CH:4][CH:3]=1.Br.[CH3:9][N:10]1[CH2:16][CH2:15][C:14]2=[CH:17][C:18](=[O:22])[C:19](=[O:21])[CH:20]=[C:13]2[CH2:12][CH2:11]1>CO>[OH:22][C:18]1[C:19]([OH:21])=[CH:20][C:13]2[CH2:12][CH2:11][N:10]([CH3:9])[CH2:16][CH2:15][C:14]=2[C:17]=1[S:7][CH2:1][C:2]1[O:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 73632-FuranmethanethiolHCID 12668031HCID 12668031, compound

Product 1

HCID 23462916HCID 23462916, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Following the procedures outlined in Example 17, 0.9 g. (0.0075 mole) of furfuryl mercaptan and 2 g. (0.0073 mole) of 3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-dione hydrobromide were reacted in 200 ml. of methanol to yield 7,8-dihydroxy-6-furfurylthio-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, free base m.p. 162°-165° C.

Sources & evidence

ORD record
ord-4c06edc0efd344a197c42d6c6f141056
Source dataset
uspto-grants-1981_05
Patent number
US04265890

Reaction notes

Loading…