Ethyl Acetoacetate → HCID 10845083, compound

HRID 2286425Notes

Reaction equation

HRID 2286425 reaction equation
[C:1]([O:7]CC)(=O)[CH2:2][C:3]([CH3:5])=O.O.[F:11][C:12]([F:17])([F:16])[CH2:13][NH:14][NH2:15]>C(O)(=O)C>[F:11][C:12]([F:17])([F:16])[CH2:13][N:14]1[C:1](=[O:7])[CH2:2][C:3]([CH3:5])=[N:15]1

Participants

4

Reactant 2

HCID 8868Ethyl AcetoacetateHCID 23463329HCID 23463329, compound

Product 1

HCID 10845083HCID 10845083, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

0.25 Mole (32.5 g) of ethyl acetoacetate and 0.25 mole (42 g) of 2,2,2-trifluoroethylhydrazine hydrate were stirred and refluxed for 2 hours in 125 ml of acetic acid. The acetic acid was distilled off in vacuo. The distillation residue was rubbed with water and recrystallized from methanol.

Workup

  1. distillationThe acetic acid was distilled off in vacuo
  2. customrecrystallized from methanol

Sources & evidence

ORD record
ord-7fcccca88f614f10b4b92ca3277309f3
Source dataset
uspto-grants-1981_05
Patent number
US04266014

Reaction notes

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