HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Hydroxy(thiophen-2-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2,2-Dibromo-1-(thiophen-2-yl)ethan-1-one | HCID 818879 | — |
| Product | Hydroxy(thiophen-2-yl)acetic acid | HCID 349855 | 77% |
Reaction Steps
The reaction was performed in the same manner as in Example 4 except that a solution of 8.0 g (200 mmol) of sodium hydroxide in 90 ml of water was used and 14.2 g (50 mmol) of 2-(dibromoacetyl)thiophene was used, gave 5.6 g of 2-thiopheneglycolic acid (yield: 77%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04266067 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-9586a7e4024146e8a3cc7629dbc232f9 |
| Source note | uspto-grants-1981_05 |