Maleic Acid → HCID 12875599, compound

Participants

Reaction Steps

6 Parts of 1-(diphenylmethyl)-N-[(6-methyl-2-pyridyl)methyl]-4-piperidinamine is dissolved in 150 parts by volume of ethyl ether and to this solution is added 100 parts by volume of the saturated solution of maleic acid in ethyl ether. The resultant mixture is filtered, the solid washed three times with 100 parts by volume portions of ethyl ether and dried in vacuo overnight at 85° C. to yield 1-(diphenylmethyl)-N-[(6-methyl-2-pyridyl)methyl]-4-piperidinamine maleate, as colorless needless melting at about 190°-191° C. after recystallization from acetonitrile. This compound has the following structural formula. ##STR36##

Provenance & Evidence