Phosphorus oxychloride → HCID 12436995, compound

Participants

Reaction Conditions

Reaction Steps

2-Phenyl-4-isothiazolium-3-one (J. Het. Chem., 8, 571 (1971)) (1 g.) is stirred at room temperature with phosphorous oxychloride (3-5 ml.); the progress of the reaction was monitored by TLC for disappearance of starting material. The reaction can be speeded up by warming to 60° C. Ether is added to precipitate a white gum. The residue was flushed once more with ether and decanted. The material is used as such in the next step.

Provenance & Evidence