3-Phenoxybenzyl alcohol → m-Phenoxybenzyl 4-(3-fluorophenyl)-2-isopropyl-3-butenoate

HRID 2286802Notes

Reaction equation

HRID 2286802 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]([CH:14]([CH3:16])[CH3:15])[C:11]([OH:13])=[O:12])[CH:5]=[CH:6][CH:7]=1.[O:17]([C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][CH:31]=1)[CH2:27]O)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]([CH:14]([CH3:16])[CH3:15])[C:11]([O:13][CH2:27][C:26]2[CH:29]=[CH:30][CH:31]=[C:24]([O:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH:25]=2)=[O:12])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 262953-Phenoxybenzyl alcoholHCID 536693764-(3-Fluorophenyl)-2-isopropyl-3-butenoic acid

Product 1

HCID 53702107m-Phenoxybenzyl 4-(3-fluorophenyl)-2-isopropyl-3-butenoate

Procedure

The acid chloride of 4-(3-fluorophenyl)-2-isopropyl-3-butenoic acid is reacted with m-phenoxybenzyl alcohol to yield m-phenoxybenzyl 4-(3-fluorophenyl)-2-isopropyl-3-butenoate, MS m/e 404 (M+).

Sources & evidence

ORD record
ord-55f63895feb041b1a5d690c07db3e10b
Source dataset
uspto-grants-1981_05
Patent number
US04267359

Reaction notes

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