HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dibutylamine → 2-Amino-5-dibutylamino-1,3,4-thiadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dibutylamine | HCID 8148 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 5-Chloro-1,3,4-thiadiazol-2-amine | HCID 314235 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-5-dibutylamino-1,3,4-thiadiazole | HCID 12899675 | — |
Reaction Steps
28 parts of dibutylamine and 25 parts of triethylamine are added to 27 parts of 2-amino-5-chloro-1,3,4-thiadiazole in 200 parts of ethanol. The reaction mixture is heated under reflux for 2 hours and then concentrated to dryness. The residue is suspended in 250 ml of water and filtered. The 2-amino-5-dibutylamino-1,3,4-thiadiazole obtained in this manner can be recrystallised from ethanol/water. Melting point: 116°-117°
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04268438 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-eaef3371ec2a4ea4a9dec2ce4d55610d |
| Source note | uspto-grants-1981_05 |