Phosgene → HCID 13400253, compound

HRID 2286842Notes

Reaction equation

HRID 2286842 reaction equation
[NH2:1][C:2]1[CH:21]=[CH:20][CH:19]=[CH:18][C:3]=1[C:4]([NH:6][NH:7][C:8](=[O:17])[C:9]1[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=1)=[O:5].[C:22](Cl)(Cl)=[O:23]>Cl>[CH3:16][O:15][C:12]1[CH:13]=[CH:14][C:9]([C:8]([NH:7][N:6]2[C:4](=[O:5])[C:3]3[C:2](=[CH:21][CH:20]=[CH:19][CH:18]=3)[NH:1][C:22]2=[O:23])=[O:17])=[CH:10][CH:11]=1

Participants

4

Reactant 2

HCID 6371PhosgeneHCID 13111448HCID 13111448, compound

Product 1

HCID 13400253HCID 13400253, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

28.5 g N-(2-amino-benzoyl)-N'-p-methoxy-benzoylhydrazine are dissolved in 800 cc 2N hydrochloric acid. A phosgene stream is passed through the solution, for a period of time of 1 hour. After purging the apparatus, the reaction product is suction filtered and washed with water. It is purified by recrystallization from isopropanol. M.P.=289° C.

Workup

  1. customAfter purging the apparatus
  2. filtrationfiltered
  3. washwashed with water
  4. customIt is purified by recrystallization from isopropanol

Sources & evidence

ORD record
ord-5c6615cf59a940b49466de0daeed85b1
Source dataset
uspto-grants-1981_05
Patent number
US04268511

Reaction notes

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