Ethanol → HCID 23460471, compound

Participants

Reaction Steps

1,2-dihydro-4-oxo-2-trichloromethylquinazoline-6-carboxylic acid (0.5 g.), ethanol (6 ml.) and concentrated sulphuric acid (3 ml.) were heated together under reflux on a steam bath for 1.5 hours. The reaction mixture was filtered, and the filtrate was poured onto a minimum quantity of ice. The precipitate thus produced was filtered off, washed with water and dried, to give ethyl 1,2-dihydro-4-oxo-2-trichloromethylquinazoline-6-carboxylate, m.p. 243°-244° C.

Provenance & Evidence