Hydrochloric Acid → HCID 178479216, compound

HRID 2286992Notes

Reaction equation

HRID 2286992 reaction equation
C([NH:4][CH2:5][CH2:6][CH2:7][N:8]1[C:12]([SH:13])=[N:11][N:10]=[N:9]1)(=O)C.[ClH:14]>>[ClH:14].[NH2:4][CH2:5][CH2:6][CH2:7][N:8]1[C:12]([SH:13])=[N:11][N:10]=[N:9]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178474793HCID 178474793, compound

Product 1

HCID 178479216HCID 178479216, compound

Procedure

A mixture of 1-(3-acetamidopropyl)-1H-tetrazole-5-thiol (85 g) and 6 N hydrochloric acid (1 l) was refluxed for 75 minutes under stirring. The reaction mixture was concentrated in vacuo and precipitates were collected by filtration and washed with hexane and diethyl ether to give 1-(3-aminopropyl)-1H-tetrazole-5-thiol hydrochloride (67.15 g).

Workup

  1. temperaturewas refluxed for 75 minutes
  2. concentrationThe reaction mixture was concentrated in vacuo
  3. customprecipitates
  4. filtrationwere collected by filtration
  5. washwashed with hexane and diethyl ether

Sources & evidence

ORD record
ord-bced465988034a37a768b9ecc7b3f6b4
Source dataset
uspto-grants-1981_05
Patent number
US04268509

Reaction notes

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